Updating the theory of mutation
Short notes on the mutation theory of de vries Hugo de Vries (1840 - 1935) was a Dutch Botanist. The Mutation theory written originally in German and later translated to English, de Vries described a number of changes and new types in many species of plants that he had studied. He collected the seeds from all these and sowed them to find out if they bred true. lamarckiana, some of the offspring showed some exceptional characters that were not present in the parents.
A similar system of ideas concerning variation and evolution was elaborated in 1899 by S. Korzhinskii, who described many proven cases of the sudden appearance of isolated, discrete hereditary changes in plants.
Medawar proposed in 1952 that aging was caused by random mutationscausing adverse aging characteristics.
In effect, aging was caused by an assortment of genetic diseases, each of which has adverse symptoms only at advanced ages.
By 1952 (and still to a much lesser extent today) many biologists considered the traditional natural selection theory to be essentially infallible, a given.
Second, if you reject Weismann's theory because most wild animals do not live long enough to die of old age, and that therefore programmed death cannot be an evolved characteristic, then you should accept Medawars idea that mutations can accumulate causing death of old age.
Each time a cell divides, there is a chance that some of the genes will be copied incorrectly. Additionally, exposures to toxins, radiation or ultraviolet light can cause mutations in your body's genes.